Education:
2004 - Master's degree in Molecular Biology with specialization in Animal and Human physiology – Sofia University "St. Kliment Ohridski"
2002 - Bachelor's degree in "Molecular Biology" – Sofia University "St. Kliment Ohridski"
Specializations:
2015-Specialization in Biochemistry, Medical University "Prof. Dr. Paraskev Stoyanov" Varna
Scientific degrees obtained and academic positions held:
2015-Educational and Scientific Degree "Doctor" in Biochemistry, Medical University "Prof. Dr. Paraskev Stoyanov" Varna
2016- Chief Assistant Professor, Administrative Assist Prof., Department of Biochemistry, Molecular Medicine and Nutrigenomics
Areas of professional interest:
Biochemistry, molecular biology; metabolic syndrome, obesity, single nucleotide polymorphisms, human intervention studies, oxidative stress, screening of medicinal plants for various biological activities, Investigation of antioxidant, anti-inflammatory, immunomodulation, antidiabetic effects of plant extracts by in vitro and in vivo methods;
Membership in scientific organizations:
Union of Scientists in Bulgaria - Section of Molecular Biology, Biochemistry and Biophysics.
European Nutrigenomics Association - NuGO
Association of Biochemical Departments in Bulgaria
Specializations and work abroad:
2009-Fifth Hand-on Course "Advanced microarray data analysis", Maastricht, The Netherlands
2009-"Protein Rainbow Workshop. The magic of DIGE." Practical Course on Quantitative Proteomics Analysis Based in 2D-Differential Gel Electrophoresis (DIGE) technology, Düsseldorf, Germany
Scientific and research activities:
Investigation of antioxidant, anti-inflammatory, immunomodulating, antidiabetic effect of biological activity of medicinal plants by in-vitro and in vivo methods, as well as the molecular mechanisms of their action. Interests in obesity and metabolic syndrome, research on genetic polymorphisms associated with them; molecular genetics and nutrigenomics.
Participation in contracts, projects, programs
"MOLECULAR MECHANISMS OF ACTION OF CYTODEОX: NEW DATA IN SUPPORT OF NEUROPROTECTIVE AND ANTIOXIDANT EFFECTS", funded by the "Science" Fund at the Medical University of Varna, Project leader Assoc. Prof. Milka Nashar, PhD, implementation period 2022-2025
„ALGOTOXINS - A NEW RISK FACTOR FOR THE QUALITY OF LIFE AND HEALTH OF PEOPLE IN BULGARIA", funded by the "Scientific Research" Fund, Project Leader Prof. Hristo Gagov, implementation period 2018-2020
"MOLECULAR MECHANISMS OF ACTION OF SULFUR-CONTAINING MINERAL WATERS FROM VARNA BASIN ON HUMAN METABOLISM WITH REGARD TO THEIR USE AS DRINKING REMEDIES", funded by the "Scientific Research" Fund, Project Leader Prof. Diana Ivanova, implementation period 2017-2018
„NUTRITECH - APPLICATION OF NEW TECHNOLOGIES AND METHODS IN NUTRITION RESEARCH – THE EXAMPLE OF PHENOTYPIC FLEXIBILITY", funded by 7FP EU, GА № 289511, Project Leader for Bulgaria Prof. Diana Ivanova, implementation period 2012-1016
"CYANOPROKARYOTES - A NEW POTENTIAL RISK FACTOR FOR MALIGNANT DISEASES IN BULGARIA?", funded by the "Scientific Research" Fund, Project Leader Prof. Maia Stoineva-Gertner, implementation period 2018-2020
"VITAMIN K-DEPENDENT GLA-PROTEINS – NEW BIOMARKERS FOR CARDIOVASCULAR CALCIFICATION", funded by the "Science" Fund at the Medical University of Varna, Project leader Prof. Bistra Tsaneva Galunska-Kaltcheva, PhD, implementation period 2017-2020
„OBTAINING OF RICH IN ANTHOCYANINS EXTRACT FROM ELDERBERRIES (Sambucus ebulus) AND CHARACTERIZING ITS BIOLOGICAL ACTIVITY IN CONNECTION WITH ESTABLISHING ADAPTOGENIC POTENTIAL IN REGARDS OF ITS USE AS A RAW MATERIAL FOR FOODS AND MEDICINAL PRODUCTS" funded by the "Science" Fund at the Medical University of Varna, Project leader Assoc. Prof. Yoana Kiselova-Kaneva, PhD
Scientific Publications
Tasinov O., Kiselova-Kaneva Y., Ivanova D., Pasheva M., Vankova D. and Ivanova D., 2021. Ferrum phosphoricum D12 Treatment Affects J774A.1 Cell Proliferation, Transcription Levels of Iron Metabolism, Antioxidant Defense, and Inflammation-related Genes. Homeopathy, online. https://doi.org/10.1055/s-0041-1731312 (IF:1.444, Q2)
Tasinov O. B., Vankova D. G., Nazifova-Tasinova N. F., Pasheva M. G., Kiselova Y. D., Sokrateva T. D., Ivanov D. L., Uzunov B. А., Stoyneva-Gärtner M. P., Ivanova D. G. 2020. Cytotoxicity of water from five Bulgarian wetlands contaminated by toxigenic cyanobacteria and cyanotoxins. Bulgarian Chemical Communications, D, 52, 257-262. (Q4).
Todorova M., Tasinov O., Pasheva M., Vankova D., Ivanova D., Galunska B., Kiselova-Kaneva Y. 2019. Cytoprotective activity of Sambucus ebulus fruit extracts in conditions of oxidative tert-buthyl-hydroperoxyde induced cell toxicity. Bulgarian Chemical Communications, 51, A, 125 – 130. (Q4)
Sokrateva T., Roussev B., Nashar M., Kiselova-Kaneva Y., Mihaylova G., Todorova M., Pasheva M., Tasinov O., Nazifova-Tasinova N., Vankova D., Ivanova D.P., Radanova M., Galunska B., Vlaykova T., Ivanova D.G. 2019. Effects of sulphur-containing mineral water intake on oxidative status and markers for inflammation in healthy subjects. Archives of Physiology and Biochemistry, (IF:2.11 (2018), Q2) DOI: 10.1080/13813455.2019.1638416.
Kiselova Y., Vankova D., Tasinov O., Feklicheva I., Potoroko I., Ivanova D. 2017. Changes in interleukin 6 and monocyte chemoattractant protein-1 expression levels in 3T3-L1 cells after exposure to Agrimonia eupatoria L. extract and subsequent oxidative stimulation with tert-Buthyl hydroperoxide reveal possible adaptogenic potential. Scripta Scientifica Pharmaceutica, 4(2): 28-34.
Vankova D, Nazifova-Tasinova N, Kiselova-Kaneva Y, Ivanova D. 2016. Stress-tolerance tests and postprandial low grade inflammation response. Scripta Scientifica Pharmaceutica, vol. 3, No. 1
Ivanova D., Nashar M., Kiselova-Kaneva Y., Tasinov O., Vankova D., Nazifova-Tasinova N. (2015). The Impact of Human Intervention Studies on the Evaluation of Medicinal Plant Antioxidant and Anti-Inflammatory Activities. Nova Science Publishers; Human Health and Nutrition: New Research, Chapter 7:145-166. ISBN: 978-1-63482-853-6.
Ivanova D, Vankova D, Nashar M. 2013. Agrimonia eupatoria tea consumption in relation to markers of inflammation, oxidative status and lipid metabolism in healthy subjects. Archives of Physiology and Biochemistry, 119(1): 32-7.
Vankova D, Radanova M, Kiselova-Kaneva Y, Madjova V, Ivanova D. 2012. The FTO rs9939609, ADIPOQ rs1501299, rs822391, and ADIPOR2 rs16928662 polymorphisms relationship to obesity and metabolic syndrome in bulgarian sample. Biotechnology & Biotechnological Equipment, V 26(1): 65-71. (IF: 0.622)
Kiselova-Kaneva Y., Tasinov O., Vankova D., Ivanova D. (2012). Ethanol induces IL-6 and TNF-α cytokine and iNOS and COX-2 enzyme gene expression in 3T3-L1 preadipocytes. Scr Sci Med V 44 (2): 31-35.
Vankova D., Ivanova D., Kiselova Y., Gerova D., Velikova V., Madjova V. (2012). Diet, lifestyle and obesity in Bulgarian sample. Science&Technologies, V 2 (1): 15-19.
Ivanova D., Tasinov O., Vankova D., Kiselova Y. (2012). Agrimonia eupatoria L. extract modulates glutamate-cysteine ligase and glutathione peroxidase expression in 3T3-L1 cells. BJAS V 19 (2):171-174.
Vankova D., Radanova M., Kiselova-Kaneva Y., Madjova V., Ivanova D. (2011). The FTO rs9939609, AdipoQ rs1501299, rs822391, and AdipoR2 rs16928662 polimorphisms relationship to obesity and metabolic syndrome in Bulgarian sample. BIOTECHNOL BIOTEC EQ, V 26 (1): 65-71. DOI: 10.5504/50YRTIMB. 0012.
Ivanova D., Tasinov O., Vankova D., Kiselova-Kaneva Y. (2011). Antioxidative potential of Agrimonia eupatoria. Science & Technologies 1 V 1 (1): 20-24.
Textbooks and educational aids:
Nashar M, Ivanova D, Galunska B, Kiselova-Kaneva Y, Vankova D, Pasheva M, Nikolova M, Nazifova-Tasinova N. Tasks and Practical Exercises in Biochemistry. Pharmacy Students Guide. Third revised and enlarged edition. Medical University - Varna 2021, ISBN 978-619-221-351-0 (in Bulgarian)
Nashar M, Ivanova D, Galunska B, Kiselova-Kaneva Y, Vankova D, Pasheva M, Nikolova M, Tasinova N. Tasks and Practical Exercises in Biochemistry. Pharmacy Students Guide. Second revised and enlarged edition. Medical University - Varna 2020, ISBN 978-619-221-280-3 (in Bulgarian)
IvanovaD., Kiselova-Kaneva Y., Galunska B., Nashar M., Vankova D. (2015). A handbook of biochemistry. Review study questions and laboratory manuals – a clinical aproach. Ris Varna Ltd. ISBN 978-954-8165-18-1.
Galunska B., Ivanova D., Vankova D., Tasinov O. (2012).Biochemistry Guide for Students in Dental Medicine. Publ. Medical University "Prof. Dr. Paraskev Stoyanov", Varna, p. 128. ISBN 978-954-9685-67-1. (in Bulgarian)
